%0 Journal Article
%T Nanotechnology and Nucleic Acids
%A Yuri M. Yevdokimov and V.V. Sytchev
%J The Open Nanoscience Journal
%D 2007
%I 
%R 10.2174/1874140100701010019]
%X The peculiarities of two approaches in the nanodesign based on the double-stranded nucleic acid molecules are considered. Main attention is devoted to the formation and properties of nanoconstructions based on the double-stranded DNA molecules and the complexes with chitosan, fixed in the spatial structure of particles of their cholesteric liquidcrystalline dispersions, and cross-linked by artificial nanobridges consisting of alternating copper ions and daunomycin molecules. In contrast to initial DNA liquid-crystalline particles, the structure of resulting nanoconstruction is not ¡°liquidcrystalline¡± any more; rather it is rigid, crystal-like, three-dimensional structure. The formed nanoconstructions possess the unique spatial and optical properties; this opens a gate for their application in biotechnology and medicine.
%U http://www.benthamscience.com/open/tonanoj/articles/V001/19TONANOJ.htm