%0 Journal Article
%T Antibody Response to Mannheimia Haemolytica Leukotoxin in Cattle with Respiratory Tract Disease
%A S. Cavirani
%A S. Taddei
%A C.S. Cabassi
%A F. Ghidini
%A C. PiancastelliC.F. FlamminiMannheimia haemolyticaM. haemolyticaM. haemolyticaM. haemolyticaM. haemolyticaM. haemolytica
%J The Open Veterinary Science Journal
%D 2007
%I Bentham Open
%R 10.2174/1874318807001010007]
%X In order to obtain data concerning the involvement of Mannheimia haemolytica in bovine respiratory disease (BRD) outbreaks, a serological survey was carried out on paired (acute- convalescent) sera from 1310 beef and 810 dairy cattle collected in 262 BRD outbreaks in Italian herds during 2002-2006. No vaccination program to M. haemolytica A1 was applied in the investigated herds. For each outbreak, 5 to 12 animals were considered for serum sampling. An enzyme linked immunosorbent assay (ELISA) was used to determine serum antibody response to M. haemolytica leukotoxin (LKT). Seroconversion involved 467 animals (22%), 314 beef cattle (24%) and 153 dairy cattle (19%), respectively. On a serological basis, M. haemolytica involvement was detected in 162 (62%) BRD outbreaks. Prevalence of seroconversion ranged from 20% to 60%. Concurrent seroconversion to M. haemolytica and the main bovine respiratory viruses was recorded in 141 (54%) outbreaks. Seroconversion to M. haemolytica LKT involved mainly cattle not vaccinated to BRD viral agents.
%U http://www.benthamscience.com/open/tovsj/articles/V001/7TOVSJ.htm