%0 Journal Article %T Ultrahigh resolution optical coherence tomography with femtosecond Ti:sapphire laser and photonic crystal fiber %A Ping Xue %A James G. Fujimoto %J Chinese Science Bulletin %@ 1861-9541 %D 2008 %I %R 10.1007/s11434-008-0235-3 %X Optical coherence tomography (OCT) with ultrahigh axial resolution was achieved by the super-continuum generated by coupling femtosecond pulses from a commercial Ti: sapphire laser into an air-silica microstructure fiber. The visible spectrum of the super-continuum from 450 to 700 nm centered at 540 nm can be generated. A free-space axial OCT resolution of 0.64 ¦Ìm was achieved. The sensitivity of OCT system was 108 dB with incident light power 3 mW at sample, only 7dB below the theoretical limit. Subcellular OCT imaging was also demonstrated, showing great potential for biomedical application. %K optical coherence tomography %K femtosecond laser %K continuum generation %K photonic crystal fiber %U http://link.springer.com/article/10.1007/s11434-008-0235-3