%0 Journal Article
%T Effects of negative emotion and its correlated neural activity on secretory immunoglobulin A
%A Fan Li
%A BuXin Han
%A Jun Ren
%A Jing Luo
%J Chinese Science Bulletin
%@ 1861-9541
%D 2008
%I 
%R 10.1007/s11434-008-0233-5
%X In this study, we investigated how the negative emotional arousal induced by watching a number of unpleasant images altered the concentration of secretory immunoglobulin A (SIgA) in saliva. Although our results found discrepancies among participants¡¯ SIgA concentration (i.e. some participants¡¯ SIgA decreased after watching unpleasant pictures, whereas others increased), further analysis revealed correlations among participants¡¯ changes in SIgA concentration, their general coping styles and their actual strategies for emotion regulation when perceiving unpleasant pictures, and the event-related potentials (ERPs) associated with viewing unpleasant pictures. The participants whose SIgA increased after watching unpleasant pictures (the ¡°Increasers¡±) had higher positive coping scores in the Trait Coping Styles Questionnaire (TCSQ) than those whose SIgA decreased (the ¡°Decreasers¡±). Also, relative to the ¡°Decreasers¡±, the ¡°Increasers¡± tended to use more emotion regulation strategies, particularly with extremely negative pictures. The amplitude of their late positive potentials (LPPs) exhibited a reverse dissociation pattern for extremely negative pictures versus least negative ones and was related to the cognitive evaluation of the stimuli¡¯s meaning. In sum, this research revealed the psychological mechanisms by which negative emotional states influence the immune system and the related ERP changes.
%K secretory immunoglobulin A
%K negative emotion
%K emotion regulation
%K cognitive reappraisal
%K LPP
%U http://link.springer.com/article/10.1007/s11434-008-0233-5