%0 Journal Article
%T Sesquilignans and sesquiterpenoid from the stem barks of Illicium simonsii and their anti-AChE activity
%A Chuan-Fu Dong
%A Lei Liu
%A Huai-Rong Luo
%A Xiao-Nian Li
%A Zheng-Ye Guan
%A Yi-Fen Wang
%J Natural Products and Bioprospecting
%@ 2192-2209
%D 2012
%I Springer
%R 10.1007/s13659-012-0026-z
%X Three new sesquilignans, 1¨C3, a new sesquiterpenoid, 4, and three known compounds were isolated from the stem barks of Illicium simonsii. The structures of new compounds (1¨C4) were elucidated by spectroscopic methods. A biosynthetic pathway was proposed for simonsienols A-C (1¨C3). Anti-AChE activity and anti-BuChE activity were evaluated for all compounds except for ¦Á-cadinol ethyl ether (4). As a result, isodunnianol (7) exhibited anti-AChE activity with an IC50 value of 13.0 ¦ÌM.
%K Illicium simonsii
%K sesquilignans
%K sesquiterpenoid
%K anti-AChE activity
%U http://link.springer.com/article/10.1007/s13659-012-0026-z