%0 Journal Article
%T Limonoids and triterpenoids from the twigs and leaves of Dysoxylum hainanense
%A Wen-Xing Liu
%A Gui-Hua Tang
%A Hong-Ping He
%A Yu Zhang
%A Shun-Lin Li
%A Xiao-Jiang Hao
%J Natural Products and Bioprospecting
%@ 2192-2209
%D 2012
%I Springer
%R 10.1007/s13659-011-0030-8
%X Four new limonoids, dysohainanins A¨CD (1¨C4), and two new triterpenoids, dysohainanins E and F (5 and 6), together with seven known ones were isolated from the twigs and leaves of Dysoxylum hainanense Merr. The structures of the new compounds were determined by a variety of spectroscopic methods. The cytotoxic activities of these compounds were evaluated, and the known compound ent-19-nor-4,16,18-trihydroxy-8(14)-pomaren-15-one (13) showed in vitro cytotoxicity against HL-60, A-549, MCF-7, and SW480 cells, with IC50 values of 24.3, 28.1, 30.7, and 22.5 ¦ÌM, respectively. Compounds 2 and 3 were tested their insecticidal activities using brine shrimp and both of them were inactive.
%K Dysoxylum hainanense
%K Meliaceae
%K limonoids
%K triterpenoids
%K cytotoxicity
%U http://link.springer.com/article/10.1007/s13659-011-0030-8