%0 Journal Article
%T The combination of Ki67, histological grade and estrogen receptor status identifies a low-risk group among 1,854 chemo-naive women with N0/N1 primary breast cancer
%A Carina Strand
%A Martin Bak
%A Signe Borgquist
%A Gunilla Chebil
%A Anna-Karin Falck
%A Marie-Louise Fj llskog
%A Dorthe Grabau
%A Ingrid Hedenfalk
%A Karin Jirstr m
%A Marie Klintman
%A Per Malmstr m
%A Hans Olsson
%A Lisa Ryd¨Śn
%A Olle St l
%A Par-Ola Bendahl and Marten Fern
%J SpringerPlus
%D 2013
%I Springer
%R 10.1186/2193-1801-2-111
%X We have confirmed a prognostic index based on a proliferation marker (Ki67), histological grade, and ER for identification of a low-risk group of patients with N0/N1 primary breast cancer. For this low-risk group constituting 57% of the patients, with a five-year distant disease-free survival of 92%, adjuvant chemotherapy will have limited effect and may be avoided.
%U http://www.springerplus.com/content/2/1/111/abstract