%0 Journal Article
%T Electrochemical behavior of adriamycin at a cobalt ion implantation modified electrode
%A Jinbo Hu
%A Qingquan Huang
%A Qilong Li
%J Chinese Science Bulletin
%@ 1861-9541
%D 2001
%I 
%R 10.1007/BF03183387
%X With Co/GCE in 0.005 mol Tris/L/0.05 mol/L NaCl solution (pH 7.1), a sensitive reductive peak of adriamgcin (ADM) was obtained by the linear scan voltammetry. The peak potential is -0.62 V (vs. SCE). The peak current is proportional to the concentration of ADM. The electrochemical behavior of the system was studied by the linear-sweep and cyclic voltammetry. The experiments showed that the reduction at Co/GCE is a quasi-reversible process with adsorption. According to Laviron¡¯s theory, the electrode reaction rate constantk 0 and the electron transfer coefficienta are determined to be 2.15 s 1 and 0.62, respectively. The composition of the surface, valence state of elements and depth distribution of elements on the surfaces of Co/GCE were determined by the X-ray photoelectron spectroscopy and Auger electron spectroscopy. The experiments showed that Co was surely implanted into the surface of GCE. The implanted Co element in the form of Co-C catalyzed the reduction of ADM.
%K adriamycin
%K ion implantation
%K modified electrode
%K electrochemical behavior
%K surface analysis
%U http://link.springer.com/article/10.1007/BF03183387