%0 Journal Article
%T Cytosporinols A-C, new caryophyllene sesquiterpenoids from Cytospora sp.
%A Yan Li
%A Chang-Wei Li
%A Cheng-Bin Cui
%A Xing-Zhong Liu
%A Yong-Sheng Che
%J Natural Products and Bioprospecting
%@ 2192-2209
%D 2012
%I Springer
%R 10.1007/s13659-012-0018-z
%X Three new caryophyllene sesquiterpenoids, cytosporinols A-C (1¨C3), have been isolated from solid cultures of Cytospora sp. The structures of 1¨C3 were elucidated primarily by NMR spectroscopy, and 3 was further confirmed by X-ray crystallography. The absolute configurations of the C-11 secondary alcohol in 1 and the 6,8-diol moiety in 3 were deduced using the modified Mosher and Snatzke¡¯s method, respectively. Compounds 2 and 3 showed moderate cytotoxicity against HeLa cells.
%K caryophyllene sesquiterpenoid
%K cytosporinol
%K Cytospora sp.
%U http://link.springer.com/article/10.1007/s13659-012-0018-z