%0 Journal Article %T Research and applications of biochip technologies %A Junquan Xu %A Xuezhong He %A Yuxiang Zhou %A Litian Liu %A Jing Cheng %J Chinese Science Bulletin %@ 1861-9541 %D 2000 %I %R 10.1007/BF02884651 %X Biochip as a new research field has enjoyed its rapid development in the past 10 years. Using microfabrication technology, thousands or hundred thousands of biological molecules can be assembled on a centimeter square microchip. Those chip-based devices can be used to analyze mutations, antigens, cells, etc. Compared with the traditional analytical instruments, chip-based micro total analytical systems have many advantages, such as reduced size, lower consumption of both reagents and energy, contamination-free, etc. Biochip technology is believed to revolutionize the future research in life sciences, disease diagnosis, drug discovery, forensic sciences and outer space exploitation in the coming century. %K biochip %K disease diagnosis %K pharmacogenomics %K laboratory-on-a-chip %U http://link.springer.com/article/10.1007/BF02884651