%0 Journal Article %T Squamous cell carcinoma arising from chronic lymphedema: case report and review of the literature %A Gomes %A Carlos Augusto %A Magalh£¿es %A Camila Beatriz Silva %A Soares Junior %A Cleber %A Peixoto %A Rodrigo de Oliveira %J Sao Paulo Medical Journal %D 2010 %I Scientific Electronic Library Online %R 10.1590/S1516-31802010000100009 %X context: squamous cell carcinoma arising from chronic lymphedema has only been reported in the literature 11 times (12 cases). some aspects of its pathogenesis remain unclear and, for the first time, attention has been drawn to epidemiological data. case report: a 90-year-old white female with chronic unilateral lower-limb lymphedema, secondary to trauma 20 years earlier, presented with a three-month history of a vegetating cutaneous lesion. there had not been any previous local ulceration. the tumor was completely excised and the histopathological analysis showed that it was an infiltrating squamous cell carcinoma. a literature review in the medline (medical literature analysis and retrieval system online) and lilacs (literatura latino-americana e do caribe em ci¨ºncias da sa¨²de) databases using the mesh (medical subject heading) terms "carcinoma, squamous cell" and "lymphedema" identified 112 references and found 12 similar case reports. %K carcinoma squamous cell %K lymphedema %K skin cancer %K angioedema %K neoplasms glandular and epithelial. %U http://www.scielo.br/scielo.php?script=sci_abstract&pid=S1516-31802010000100009&lng=en&nrm=iso&tlng=en