%0 Journal Article %T Resultados actuales de la pancreatoduodenectom¨ªa para el tratamiento de los tumores periampulares y an¨¢lisis de factores pron¨®sticos de sobrevida %A Norero %A Enrique %A Vi£¿uela %A Eduardo %A B¨¢ez %A Sergio %A Mart¨ªnez %A Cristian %A Reyes %A Julio %A Kusanovic %A Rodrigo %A Sanhueza %A Marcel %A Aguayo %A Gloria %A Calvo %A Alfonso %A Mege %A Rose Marie %A Caracci %A Mario %A D¨ªaz %A Alfonso %J Revista m¨¦dica de Chile %D 2011 %I Sociedad M¨¦dica de Santiago %R 10.4067/S0034-98872011000800006 %X background: the diagnosis and treatment of periampullary tumors represents a challenge for current medicine. aim: to review the results of pancreaticoduodenectomy (pdd) in the treatment of periampullary tumors and to identify risk factors that impact the long-term survival. patients and methods: we performed a retrospective study of patients who underwent a pdd for periampullary tumors between 1993 and 2009. we reviewed perioperative results and long term survival. we performed a multivariate analysis for long-term survival. results: a pdd was performed in 181 patients aged 58 ¡À 12 years (98 females). piloric preservation was done in 53% and a pancreatogastric anastomosis was used in 94% of cases. morbidity was 62% and postoperative mortality was 5.5%. pancreatic cancer was the most frequent pathological finding in 41%, followed by ampullary cancer in 28% and distal bile duct cancer in 16%. median survival was 17 months, with a five years survival of 24%. survival for ampullary tumors was 28 months with a five years survival of 32%. the median and five years survival were 14 months and 16% for bile duct cancer and 11 months and 14% for pancreatic cancer. multivariate analysis identified tumor type (pancreas /bile duct) and lymph node dissemination as independent predictors of mortality. conclusions: one quarter of patients experienced long term survival. mortality predictors were tumor type and lymph node dissemination. %K common bile duct neoplasms %K pancreaticoduodenectomy %K pancreatic neoplasms. %U http://www.scielo.cl/scielo.php?script=sci_abstract&pid=S0034-98872011000800006&lng=en&nrm=iso&tlng=en