%0 Journal Article
%T Uso de la metformina en el tratamiento de pacientes inf¨¦rtiles con s¨ªndrome de ovarios poliqu¨ªsticos
%A Giustiniano
%A Belvian
%A Rodr¨ªguez
%A Sheila
%A Abache
%A Enrique
%A Hurtado
%A F¨¦lix
%J Revista de Obstetricia y Ginecolog¨ªa de Venezuela
%D 2010
%I Sociedad de Obstetricia y Ginecolog¨ªa de Venezuela
%X objective: to determine the effect of treatment with metformin in infertile patients with polycystic ovary syndrome. methods: clinical, prospective and descriptive study. infertile anovulatory patients with polycystic ovary syndrome and insulin resistant were included, and all of them, were treated with metformin for 3 months. patients who did not ovulate in this time, received clomiphene citrate for 6 months. setting: fertility service of maternidad "concepcion palacios". results: 62 infertile patients were included in this study. the pregnancy rate was 25.8 % (19 patients). the 57.9 % of women became pregnant with metformin administration for 3 months, with p= 0.492, it was not statistical significance. the pregnancy rate with clomiphene citrate was 23.5 % (8 patients), p= 0.684. the abortion rate was 26.3 % (5). conclusion: the metformin induce ovulation in anovulatory polycystic ovary syndrome women, whereas the pregnancy rate resulted similar in both treatment groups: metformin alone and metformin and clomiphene citrate.
%K metformin
%K clomiphene citrate
%K polycystic ovary syndrome
%K insulin resistant.
%U http://www.scielo.org.ve/scielo.php?script=sci_abstract&pid=S0048-77322010000400005&lng=en&nrm=iso&tlng=en