%0 Journal Article
%T Bovine S protein (vitronectin) increases phagocytosis of Streptococcus dysgalactiae
%A Filippsen
%A Laerte Francisco
%J Revista de Microbiologia
%D 1999
%I Scientific Electronic Library Online
%R 10.1590/S0001-37141999000100003
%X the effects of bovine s protein (vitronectin) on phagocytosis of streptococcus dysgalactiae strains isolated from cattle with mastitis were investigated. phagocytized streptococci were determined by a fluorometric microassay using glass adherent polymorphonuclear neutrophils (pmn). preincubation of s. dysgalactiae with bovine s protein significantly increased their phagocytosis by pmn. bovine s protein had no effect on phagocytic killing of non-s protein binding s. pyogenes cultures. enzymatic digestion of the bovine s protein binding sites on s. dysgalactiae with pronase resulted in a significative reduction of the effects of s protein on phagocytosis. it could thus be concluded that in addition to its role as a promoter of cellular adhesion and complement inhibitor, bovine s protein may also influence the phagocytosis of s. dysgalactiae during inflammatory processes.
%K streptococcus dysgalactiae
%K bovine s protein
%K phagocytosis
%K bovine mastitis.
%U http://www.scielo.br/scielo.php?script=sci_abstract&pid=S0001-37141999000100003&lng=en&nrm=iso&tlng=en