%0 Journal Article %T Paracoccidioidomycosis in the state of Maranh£¿o, Brazil: geographical and clinical aspects %A Matos %A Wilma Batista de %A Santos %A Gisele Maria Campelo dos %A Silva %A Vitor Emmanuel Bou£¿as da %A Gon£¿alves %A Elo¨ªsa da Gra£¿a do Ros¨¢rio %A Silva %A Antonio Rafael da %J Revista da Sociedade Brasileira de Medicina Tropical %D 2012 %I Sociedade Brasileira de Medicina Tropical - SBMT %R 10.1590/S0037-86822012000300020 %X introduction: the study aimed to show the situation of paracoccidioidomycosis in the state of maranh£¿o, brazil. methods: this study is a descriptive case series developed in two stages. first, a survey of cases originating from the state of maranh£¿o at the instituto de doen£¿as tropicais natan portela, piau¨ª (idtnp) from 1997 to 2007, and second, the clinical description of 29 cases diagnosed in the centro de refer¨ºncias em doen£¿as infecciosas e parasit¨¢rias, maranh£¿o (credip) from 2004 to 2010. results: two hundred and sixteen cases have been cataloged at the idtnp. west, east, and central regions of the state of maranh£¿o recorded 90.3% of cases proving to be important areas for study. the western region, with a prevalence of 10.8/100,000 inhabitants, has a significantly higher proportion of cases than the northern, southern, and eastern regions (p < 0.05). the occurrence was higher in men with 89.3% of cases, and the male-to-female ratio was 8.4:1. the majority of patients were older than 20 years, lived in rural areas, and had farming or soil management as main occupation (73.8%). at credip, 29 cases were diagnosed, of which 26 (89.6%) had multifocal manifestations. mucous tissues were involved more (75.8%) frequently, followed by lymph nodes, skin, and lungs with 65.5%, 39% and 37.9 %, respectively. the diagnosis was made by combining direct examination, culture, and histopathology. conclusions: the study shows the geographical distribution and the epidemiological and clinical aspects of paracoccidioidomycosis, revealing the significance of the disease to the state of maranh£¿o. %K paracoccidioidomycosis %K state of maranh£¿o %K epidemiology. %U http://www.scielo.br/scielo.php?script=sci_abstract&pid=S0037-86822012000300020&lng=en&nrm=iso&tlng=en