%0 Journal Article %T Human Leukocyte Antigens and HIV Type 1 Viral Load in Early and Chronic Infection: Predominance of Evolving Relationships %A Jianming Tang %A Rakhi Malhotra %A Wei Song %A Ilene Brill %A Liangyuan Hu %A Paul K. Farmer %A Joseph Mulenga %A Susan Allen %A Eric Hunter %A Richard A. Kaslow %J PLOS ONE %D 2012 %I Public Library of Science (PLoS) %R 10.1371/journal.pone.0009629 %X During untreated, chronic HIV-1 infection, plasma viral load (VL) is a relatively stable quantitative trait that has clinical and epidemiological implications. Immunogenetic research has established various human genetic factors, especially human leukocyte antigen (HLA) variants, as independent determinants of VL set-point. %U http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0009629