%0 Journal Article
%T Caracter¨ªsticas cl¨ªnicas del P¨²rpura Trombocitop¨¦nico Inmune: revisi¨®n de 52 casos
%A Sotomayor F
%A Cristi¨¢n
%A Kopp G
%A Katherine
%A Cavieres A
%A Mirta
%A Dal Borgo A
%A Patricia
%A Silva C
%A Rosario
%J Revista chilena de pediatr¨ªa
%D 2006
%I Sociedad Chilena de Pediatr¨ªa
%R 10.4067/S0370-41062006000100004
%X background: inmune thrombocytopenic purpura (itp) is usually self-limited, but may have a chronic evolution when persisting more than 6 months (10-20% cases). its treatment is controversial and few national data is available. objective: to obtain knowledge on clinical and laboratory characteristics of itp, its relationship with chronic evolution and treatment. patients and methods: retrospective study that includes patients with diagnosis of itp between march 1998 and february 2003 at luis calvo mackenna children's hospital. we registered at diagnosis: sex, age, symptoms and treatment strategy. platelet count (pc) was done at diagnosis, between day 15-60 and after 6 months. fisher test and odds ratio were calculated. results: median age was 4,4 years (0,7-16,1), initial pc was ¡ê 20 000/mm3 in 37/52 cases. no cerebral bleeding was found. observation strategy was used in 34/52 cases, steroids in 17/52 cases and steroids + inmunoglobulin in 1 case. the 6-months follow up was completed in 48/52 cases; 11 patients had a chronic evolution. we found an association with pc day 15 ¡ê 20 000/mm3 (p = 0,01 or = 9 ic95% 1,26-80,16) and pc day 60 ¡ê 50 000/mm3 (p = 0,0000003 or = 124 ic95% 7,77-4951,52). conclusions: most of our patients were successfully managed with the observation strategy. 23% cases had a chronic evolution and pc day 15 ¡ê 20 000/mm3 and pc day 60 ¡ê 50 000/mm3 are considered risk factors
%K acute immune thrombocytopenic purpura
%K chronic immune thrombocytopenic purpura
%K outcome
%K treatment.
%U http://www.scielo.cl/scielo.php?script=sci_abstract&pid=S0370-41062006000100004&lng=en&nrm=iso&tlng=en