%0 Journal Article
%T Development of Low-Cost Inverted Microscope to Detect Early Growth of Mycobacterium tuberculosis in MODS Culture
%A Mirko Zimic
%A Abner Velazco
%A Germ¨˘n Comina
%A Jorge Coronel
%A Patricia Fuentes
%A Carmen G. Luna
%A Patricia Sheen
%A Robert H. Gilman
%A David A. J. Moore
%J PLOS ONE
%D 2012
%I Public Library of Science (PLoS)
%R 10.1371/journal.pone.0009577
%X The microscopic observation drug susceptibility (MODS) assay for rapid, low-cost detection of tuberculosis and multidrug resistant tuberculosis depends upon visualization of the characteristic cording colonies of Mycobacterium tuberculosis in liquid media. This has conventionally required an inverted light microscope in order to inspect the MODS culture plates from below. Few tuberculosis laboratories have this item and the capital cost of $5,000 for a high-end microscope could be a significant obstacle to MODS roll-out.
%U http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0009577