%0 Journal Article
%T Functional Glycosylation of Dystroglycan Is Crucial for Thymocyte Development in the Mouse
%A Li-Ying Liou
%A Kevin B. Walsh
%A Arineh R. Vartanian
%A Daniel Beltran-Valero de Bernabe
%A Megan Welch
%A Kevin P. Campbell
%A Michael B. A. Oldstone
%A Stefan Kunz
%J PLOS ONE
%D 2012
%I Public Library of Science (PLoS)
%R 10.1371/journal.pone.0009915
%X Alpha-dystroglycan (¦Á-DG) is a cell surface receptor providing a molecular link between the extracellular matrix (ECM) and the actin-based cytoskeleton. During its biosynthesis, ¦Á-DG undergoes specific and unusual O-glycosylation crucial for its function as a high-affinity cellular receptor for ECM proteins.
%U http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0009915