%0 Journal Article %T Influenza pand¨¦mica A (H1N1) 2009: epidemiolog¨ªa, caracter¨ªsticas cl¨ªnicas y diferencias con influenza estacional en Chile %A Rabagliati B %A Ricardo %A Siri Z %A Leonardo %A P¨¦rez C %A Carlos M %A Labarca L %A Jaime %A Ferr¨¦s G %A Marcela %J Revista chilena de infectolog¨ªa %D 2011 %I Sociedad Chilena de Infectolog¨ªa %R 10.4067/S0716-10182011000700006 %X pandemic influenza a (h1n1) 2009 raised questions regarding differences with seasonal influenza. objectives: to describe the clinical features of pandemic influenza and compare them to seasonal influenza. patients y methods: a descriptive study that compared hospitalized adults was done between patients with confirmed pandemic inluenza in the hospital cl¨ªnico universidad cat¨®lica in santiago, chile, from may to july 2009 and 95 confirmed historic cases of seasonal influenza. results: 54 patients with pandemic influenza were included, 51.9% were male, age of 52.8 ¡À 19.5 years old; 79.6% had chronic diseases; 16.7% were immunocompromised patients and 7.4% of pregnant women. 25.9% of the patients acquired the infection during the hospitalization. 31.5% were admitted to intermediate/intensive care units. pneumonia was diagnosed in 37%, and the mortality rate was 3.7%. the comparison between pandemic and seasonal influenza showed less proportion of patient > 65 years of age (31.5% vs. 68%; p < 0.0001); double number of nosocomial acquisition and more cases of pneumonia and death. conclusions: the pandemic inluenza infection affected younger people and was related with more nosocomial cases, pneumonia and mortality rates than seasonal inluenza. %K pandemic inluenza %K a (h1n1) %K seasonal inluenza. %U http://www.scielo.cl/scielo.php?script=sci_abstract&pid=S0716-10182011000700006&lng=en&nrm=iso&tlng=en