%0 Journal Article
%T Detecci¨®n precoz por Tomograf¨ªa Computada Cuantitativa Multicorte de alteraciones en la densidad mineral ¨®sea, inducidas por una dieta aterog¨¦nica, en un modelo experimental en ratas en crecimiento
%A Gubert
%A Marcelo Joaqu¨ªn
%A Monforte
%A Fabi¨¢n
%A Calo
%A Claudia
%A Friedman
%A Silvia Mar¨ªa
%A Lylyk
%A Pedro
%A Gamba
%A Carlota Alicia
%J Revista argentina de radiolog£¿-a
%D 2012
%I Scientific Electronic Library Online
%X purpose. to dem¨®nstrate the utility of multislice quantitative computed tomography (ms-qct) in the early detection of mandibular bone mineral density (bmd) alterations induced by an atherogenic diet in a growing rat experimental model. materials and methods. male weanling wistar rats (n =16) were divided by body weight (wt) into 2 groups: control (c) and experimental (e), with no significant differences in the mean initial wt (p>0.05). c was fed rodent stock diet ad libitum, and e an atherogenic diet for 3 weeks (3w). zoometry (body weight and length) and diet intake (g/loog rat/day) were monitored. at 3 w in serum (mg/dl) lipid-lipoprotein profile was studied: total cholesterol (t-c), triglycerides (tg), high-density lipoprotein cholesterol (hdl-c), non-hdl cholesterol (non-hdl-c) and ms-qct (philips 64 ct, quantified with the efilm workstation 2.1) in seven mandibular ¨¢reas (ma): n¡ãlto 4: from chin to mandibular foramen, n¡ã 5: coronoid process, n¡ã 6: condylar process, n¡ã 7: angular process. statistics: pearson's correlation between bmd in each ma and serum t-c. p<0.05 was considered significant. results. (mean ¡À sd) at 3w, neither zoometric £¿or intake differences were observed (p>0.05). correlation coefficients (r) and their significance lev¨¦is (p) were relevant in 5/7 ma. ma1-.-0.580 (p=0.019), ma2:-0.709 (p=0.002), ma3:-0.635 (p=0.008), ma5:-0.674 (p=0.004), ma6:-0.564 (p=0.023). conclusions. these results suggest that ms-qct is an imaging diagnostic method that allows the early detection of mandible bone architecture alterations induced by an atherogenic diet. inverse correlation between bmd and t-c would ind¨ªcate an association between an atherogenic diet intake and potential temporomandibular disorders.
%K atherogenic diet
%K bone architecture
%K quantitative computed tomography
%K rat mandible.
%U http://www.scielo.org.ar/scielo.php?script=sci_abstract&pid=S1852-99922012000100007&lng=en&nrm=iso&tlng=en