%0 Journal Article
%T Endocarditis infecciosa por S. aureus en la Argentina: EIRA 2. An¨¢lisis comparativo luego de 10 a£¿os de los estudios EIRA 1 y 2
%A Ferreir¨®s
%A Ernesto R.
%A Casab¨¦
%A Jos¨¦ H.
%A Nacinovich
%A Francisco
%A Swieszkowski
%A Sandra
%A Cohen Arazi
%A Hern¨¢n
%A Cort¨¦s
%A Claudia
%A Modenesi
%A Juan Carlos
%A Varini
%A Sergio
%J Revista argentina de cardiolog£¿-a
%D 2006
%I Scientific Electronic Library Online
%X work objective to analyze the evolution and profile of infective endocarditis (ie) in argentina during the last 10 years through the comparison of eira-1 and eira-2 surveys. to determine the epidemiological and clinical characteristics, and in-hospital evolution of s. aureus ie (saie) in argentina. research design and methods the eira-2 survey was a prospective, multicentric study performed in 82 hospitals belonging to 16 of the 24 argentinean provinces. patients with definitive diagnosis of ie (duke criteria) were followed-up during an 18-month period. results three hundred and ninety episodes of definitive ie were reported (108 saie and 282 non-saie); mean age was 58.5¡À17.3 years, male sex 70%. no statistically significant differences were observed between saie and non-saie regarding mean age, sex, prosthetic valve ie, degenerative valve ie, prevalence of heart failure and surgical treatment. the comparison of the eira-2 and eira-1 surveys showed that ie profile has changed in the last decade in argentina. currently, patients are older (58 vs. 51 years), and have a higher prevalence of underlying heart disease (67% vs. 55%) particularly prosthetic valve (19.2% vs. 8.5%), degenerative valve disease (12.4% vs. 4.8%), and congenital heart disease (9.5% vs. 4.2%); infections were more frequently caused by s. aureus (30% vs. 26%) and less by s. viridans (30.8% vs. 26.8%) with a decreased time until final diagnosis (21.5 vs. 33 days). no significant changes were observed in the overall mortality rate. patients with saie showed a significantly (p< 0.01) higher prevalence of underlying heart disease (58.3% vs. 67.4% [or 0.7; 95%ci: 0.4-0.99]); and a lower incidence of rheumatic valve disease [0.9% vs. 7.1% (or 0.1; 95%ci: 0.01-0.9)] and congenital heart disease [3.7% vs. 11.7% (or 0.29; 95%ci: 0.08-0.9)]. prior invasive procedures (33.3% vs. 22% [or 1.8; 95%ci: 1.1-3.0]) and hemodialysis (21.3% vs. 10.6% [or 2.2; 95%ci: 1.2-4.3]) were significantly more frequent in saie;
%K endocarditis
%K epidemiology
%K s. aureus
%K hospital mortality.
%U http://www.scielo.org.ar/scielo.php?script=sci_abstract&pid=S1850-37482006000100008&lng=en&nrm=iso&tlng=en