%0 Journal Article
%T Dislipidemia y disfunci¨®n tiroidea en ni£¿os y adolescentes con diabetes mellitus tipo 1: Relaci¨®n con el control metab¨®lico e ¨ªndice de masa corporal
%A Brice£¿o
%A Yajaira
%A Paoli
%A Mariela
%A Maulino
%A Nora
%A Gaffaro de Valera
%A Loida
%A Marcano
%A Henry
%A P¨¦rez
%A Marvelys
%J Revista Venezolana de Endocrinolog¨ªa y Metabolismo
%D 2009
%I Sociedad Venezolana de Endocrinolog¨ªa y Metabolismo
%X objetive: to determine the prevalence of thyroid dysfunction and dyslipidemia in children and adolescents with type 1 diabetes mellitus (1dm), from the children£¿s hospital jm de los r¨ªos, and its association with metabolic control and body mass index. methods: a descriptive and retrospective study was done. data were obtained from the medical records of patients with 1dm, who attended during a period of 3 years (2004 to 2006). the following data were collected: age, sex, duration of diabetes, body mass index (bmi), metabolic control (hba1c), presence of antithyroid antibodies, thyroid and lipid profile. results: the 53.4% were female, 46,6% male, twenty two (8.7%) preschoolers, 80 (31.6%) school children and 151 (59.7 %) adolescents. a good metabolic control was observed in 22.8% and poor control in 77.2% of the patients. it was noted that the older the worse metabolic control (p=0.02). there was a significant positive correlation of hba1c values with bmi and duration of dm1. the 69,6% had some form of dyslipidemia and the frequency of atherogenic lipid profile was significantly higher in patients poorly controlled. significantly higher values of ct, c-ldl, triglycerides and tg/hdl-c ratio were observed in diabetics in poor metabolic control. the values of tc and ldl-c were significantly higher in the obese group compared with normal and overweight subjects. antithyroid antibodies were positive in 12.7% of the patients. the 6% were hypothyroid and there was not association with the frequency of dyslipidemia or the metabolic control. conclusion: the frequency of dyslipidemia and hypothyroidism in children and adolescents with 1dm was similar to that reported in the literature. it was demonstrated a clear association of dyslipidemia with poor metabolic control and obesity. we recommend the determination of lipids and thyroid function in patients with type 1 dm.
%K type 1 diabetes mellitus
%K dyslipidemia
%K thyroid dysfunction.
%U http://www.scielo.org.ve/scielo.php?script=sci_abstract&pid=S1690-31102009000300005&lng=en&nrm=iso&tlng=en