%0 Journal Article
%T Relaci¨®n entre conductancias de sodio y potasio al estilo Hodgkin y Huxley y su efecto en la propagaci¨®n de potenciales de acci¨®n a 40ˇăC
%A Hern¨˘ndez Bustos
%A Oscar Emilio
%A Hern¨˘ndez Bustos
%A Lilibeth
%J Revista Salud Uninorte
%D 2011
%I Universidad del Norte
%X objetive: to determine from computational simulation, the response of an unmielynate axon to a constant current stimulus for different hh style maximum sodium (gn) and potassium (gk) conductance in the space gnavs. gksuch that 0s/cm2<gna<6.4s/cm2 and 0s/cm2<gk<2s/cm2 at 40c methodology: the propagation of action potentials along a neuronal structure called neurox was simulated using the software neuron. passive properties and hh style sodium and potassium channels whose opening and closing rates were corrected with the thermic coefficient, were inserted in neurox. results: there is a region of dots in the space gnavs. gkthat are limited by the lines and on which one unique action potential is spread along the neurox at 40ˇăc. conclusion: hh style sodium and potassium conductance can exist in neurons that work at 40ˇăc, with diverse possibilities of combinations of gnaand gkthat overcome the restrictions imposed by increment of speed in the opening and closing of the corresponding channels. this work established a methodological reference for exploring other areas of combinations of conductances.
%K hh style sodium and potassium conductance
%K temperature
%K simulation
%K propagation
%K action potential.
%U http://www.scielo.org.co/scielo.php?script=sci_abstract&pid=S0120-55522011000200007&lng=en&nrm=iso&tlng=en