%0 Journal Article
%T Oxpholipin 11D: An Anti-Inflammatory Peptide That Binds Cholesterol and Oxidized Phospholipids
%A Piotr Ruchala
%A Mohamad Navab
%A Chun-Ling Jung
%A Susan Hama-Levy
%A Ewa D. Micewicz
%A Hai Luong
%A Jonathan E. Reyles
%A Shantanu Sharma
%A Alan J. Waring
%A Alan M. Fogelman
%A Robert I. Lehrer
%J PLOS ONE
%D 2012
%I Public Library of Science (PLoS)
%R 10.1371/journal.pone.0010181
%X Many Gram-positive bacteria produce pore-forming exotoxins that contain a highly conserved, 12-residue domain (ECTGLAWEWWRT) that binds cholesterol. This domain is usually flanked N-terminally by arginine and C-terminally by valine. We used this 14-residue sequence as a template to create a small library of peptides that bind cholesterol and other lipids.
%U http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0010181