%0 Journal Article
%T Efecto diur¨¦tico de extractos acuosos y alcoh¨®licos de flores de Phrygilanthus acutifolius (corpo) en ratas
%A Habib Intersimone
%A Natalia
%A Daud Thoene
%A Adriana
%A S¨˘nchez Riera
%A Alicia
%J Revista Cubana de Plantas Medicinales
%D 2005
%I ECIMED
%X an experimental study was conducted in wistar rats, to evaluate the potential diuretic effect of aqueous and ethanol extracts of flowers from phrygilanthus acutifolius (ruiz & pav.) eichler in doses of 200 and 400 mg/kg of body weight. results were compared to those obtained from furosemide in dose of 20 mg/kg of body weight (reference diuretic) and saline solution (negative control). urinary excretion was measured at 24 h, and the concentration of na+ , k+ , cl- , ca2+ and p was determined in the final volume. diuretic action of extracts from phrygilanthus acutifolius was confirmed. aqueous and ethanol extracts at the dose of 200 mg/kg of body weight demonstrated more natriuretic activity than the others studied doses. on comparing them with furosemide, it was observed that the excretion of potassium in urine decrease, which suggested a diuretic action acting as potassium savers. further researches are necessary to elucidate the mechanism of diuretic action of the analyzed extracts.
%K phrygilanthus acutifolius
%K plant extracts
%K diuretics
%K medicinal plants
%K furosemide.
%U http://scielo.sld.cu/scielo.php?script=sci_abstract&pid=S1028-47962005000300003&lng=en&nrm=iso&tlng=en