%0 Journal Article %T Solubilizaci車n de componentes de membrana externa de Leptospira interrogans serovar mozdok mediante desoxicolato de sodio y trit車n X-100 y evaluaci車n de su capacidad inmunog谷nica y protecci車n hom車loga y heter車loga inducida en hamsters %A Fern芍ndez Rivera %A Yovania %A Pino Navarro %A Yadira %A Aranguren Mazorra %A Yisabel %A Gonz芍lez Rodr赤guez %A Andr谷s %A Padr車n %A Mar赤a de los 芍ngeles %A Vald谷s %A Yolanda %J Revista Cubana de Medicina Tropical %D 2005 %I Centro Nacional de Informaci車n de Ciencias M谷dicas %X two detergents (triton x-100 and sodium desoxycholate) were evaluated as solubilizing agents of the components of the outer membrane of leptospira pomona serovar mozdok. it was obtained a greater yielding of proteins on applying the treatment with triton x-100. the variants formulated starting from the extracts obtained showed a high immunogenicity and capacity of homologous protection against the challenge in hamster. %K leptospira %K outer membrane proteins %K triton x-100 %K immunogenicity %K protection. %U http://scielo.sld.cu/scielo.php?script=sci_abstract&pid=S0375-07602005000100013&lng=en&nrm=iso&tlng=en