%0 Journal Article %T Escalado de la fermentaci¨®n de Leptospira interrogans canicola canicola para la producci¨®n de la vacuna vax-SPIRAL %A Ben¨ªtez Zamora %A Jos¨¦ Daniel %A Fern¨¢ndez Enrique %A Kenia %A Guti¨¦rrez Bou¨¦ %A Ra¨²l %A Hern¨¢ndez Torres %A Florinda %A Lazo Airado %A Janet %A Rojo Hern¨¢ndez %A Dami¨¢n %J Revista Cubana de Medicina Tropical %D 2005 %I Centro Nacional de Informaci¨®n de Ciencias M¨¦dicas %X the operational conditions for the production of vaccine vax-spiral were established at the scale of 100 l. it was concluded that it should be carried out with an air flow of 10 l/min (0.1 vvm) and without mechanical agitation. %K vax-spiral %K fermentation %K leptospirosis. %U http://scielo.sld.cu/scielo.php?script=sci_abstract&pid=S0375-07602005000100022&lng=en&nrm=iso&tlng=en