%0 Journal Article
%T Efectos locales de la aplicaci¨®n del n-butil 2-cianoacrilato en la microcirug¨ªa vascular experimental
%A Carral Novo
%A Juan
%A Gueorguievna Rozhkova
%A Galina
%A Rodr¨ªguez Sosa
%A V¨ªctor
%A Sebazco Pernas
%A Caridad
%A Ca£¿izares Graupera
%A Maria Elena
%A Montero Gonz¨¢lez
%A Teresita
%A Alfonso Alfonso
%A L¨¢zaro
%J Revista Cubana de Medicina Militar
%D 2006
%I ECIMED
%X a retrospective randomized cohort study (at one and six months) was performed in 65 male wistar rats divided into healthy controls (n= 10), study (n= 28) and positive controls (n= 27). it evaluated the advantages of n-butyl 2-cyanoacrylate adhesive in vascular microsurgery, compared suture time between this adhesive and polypropylene 8/0, assessed suture strength, determined anastomosis permeability and differentiated the vascular histological behaviour. the adhesive was applied in abdominal aorta of rats with 3 retention stitches, intraluminal pressure was measured using conventional barometric techniques, vascular histological behaviour was analyzed and compared with the application of polypropylene 8/0. vascular suture time using the adhesive was 836,29 ¡À 77,18 s in the study group and 2634,07 ¡À 97,30 in positive controls, with highly statistical significance (p < 0,000000); allowed pressure with the adhesive, 296,95 ¡À 6,79mmhg and 252,61 ¡À 58,71 mmhg in positive controls, with highly statistical significance (p < 0,00544); suture effectiveness was 92,86 % with n-butyl 2-cyanoacrylate and 85,19% with polypropylene, without any differences observed in both groups. cyanoacrylate degraded after 6 months. n-butyl 2-cyanoacrylate was quicker to be applied in vascular surgery, stands more pressure and causes no toxicity.
%K cyanoacrylates
%K microsurgery
%K vascular surgery.
%U http://scielo.sld.cu/scielo.php?script=sci_abstract&pid=S0138-65572006000300005&lng=en&nrm=iso&tlng=en