%0 Journal Article %T Detecci¨®n de respuesta linfoproliferativa en monos inoculados con virus dengue 4 %A Garc¨ªa %A Gissel %A ¨¢lvarez %A Mailing %A Santana %A Elaine %A Mart¨ªnez %A Jos¨¦ Rafael %A ¨¢lvarez %A Alejandro %A Rodr¨ªguez %A Rosmary %A Guzm¨¢n %A Mar¨ªa G. %J Revista Cubana de Medicina Tropical %D 2003 %I Centro Nacional de Informaci¨®n de Ciencias M¨¦dicas %X a group of 6 cynomolgus monkeys was immunized with dengue 4 virus (h247 standard strain). 60 days after innoculation the cellular proliferation against the same serotype as well as against hetereologous serotypes 1 and 2 was measured. a proliferative response predominantly of the specific serotype and some cross reactivity were detected. these results showed a behavior of primates similar in some extent to that of human beings and mice regarding the specific serotype and cross serotype response to dengue virus. %K dengue virus [immunology] %K dengue [immunology] %K macaca fascicularis %K disease models %K animal: t-lymphocytes [immunology]. %U http://scielo.sld.cu/scielo.php?script=sci_abstract&pid=S0375-07602003000100004&lng=en&nrm=iso&tlng=en