%0 Journal Article %T Nuevas alternativas de inmovilizaci¨®n de activos antioxidantes %A Gelabert Rodr¨ªguez %A Yanet Esperanza %A D¨ªaz Gonz¨¢lez %A Rodolfo %J Revista Cubana de Investigaciones Biom£¿£¿dicas %D 2001 %I ECIMED %X during the last few decades, emphasis has been made on the development of new immobilization systems that allow to extend lifetime of a substance so as to improve its efficacy. at present, the most used systems for controlling the release of active principles are encapsulation systems (liposomes) and sequestering or matrix systems (nanosfers). both are immobilization alternatives because of their chemical composition, their possibility of adding substances with well-defined chemical characteristics, the change of these structures¡ä surface and the incorporation of functional groups, which allows to direct the intact actives to the site of action, and the feasibility of obtaining preparations with different surface charge, size and fluidity depending on the objective of the work. they present a characteristic active release kinetics. these systems have opened up new opportunities for the immobilization of antioxidant actives and their use in cosmetics as well as in biomedicine for the diagnosis and treatment of various diases %K liposomes [therapeutic use] %K antioxidants [therapeutic use] %K cosmetics %K sunscreening agents. %U http://scielo.sld.cu/scielo.php?script=sci_abstract&pid=S0864-03002001000100015&lng=en&nrm=iso&tlng=en