%0 Journal Article
%T Eficiencia del proceso de lavado en la obtenci¨®n del citrato de calcio y magnesio a escala de banco
%A Rodr¨ªguez Chanfrau
%A Jorge E
%A Lagarto Parra
%A Alicia
%A Bueno Pav¨®n
%A Viviana
%A Guerra Sardi£¿a
%A Isbel
%A Vega Hurtado
%A Yamilet
%J Revista Cubana de Farmacia
%D 2010
%I ECIMED
%X as part of the technological process optomization to obtain calcium citrate and magnesium from dolomites, we studied at bench scale, the washout stage to decrease the free citric acid content. washout variants allowed to decrease the free citric acid content under 3 %, whereas the calcium and magnesium values are similar to those of batch before to carry out the wahout process. on the other hand, toxicity study in rats, proved that the batches where different washout variables were applied not provoke gastric irritability at doses of 2 000 mg/kg of body weight confirming that above mentioned established process is approproate to guarantee the raw material quality.
%K calcium citrate and magnesium
%K washout
%K dolomite
%K citric acid.
%U http://scielo.sld.cu/scielo.php?script=sci_abstract&pid=S0034-75152010000100002&lng=en&nrm=iso&tlng=en