%0 Journal Article %T Estudio de preformulaci¨®n del citrato de dietilcarbamazina %A Le¨®n Rodr¨ªguez %A Rafael %A Gonz¨¢lez Calzadilla %A Alexander %A Mart¨ªnez ¨¢lvarez %A Luis %A Roberto Cordov¨¦s %A Yamilka %J Revista Cubana de Farmacia %D 1999 %I ECIMED %X the study of diethycarbamazine citrate preformulation with a view to finding uot the physico - chemical and tachnological characteristics of this pharmaceutical for further production of a 50 mg tablet was performed. this study included the determination of the size of micronized and non-micronized particles by optical microscopy in which the influence of size on the pharmaceutical dissolving in vitro was shown. drug - excipient incompatibility was analysed using differential scannig calorimetry and no interaction was found under experimental working conditions. other physico-chemical & technological properties of this pharmaceutical were examined. %K diethycarbamazine [chemistry] %K filarcides [chemistry] %K chemistry %K pharmaceutical. %U http://scielo.sld.cu/scielo.php?script=sci_abstract&pid=S0034-75151999000200004&lng=en&nrm=iso&tlng=en