%0 Journal Article
%T Pasteurizaci¨®n de soluciones de inmunoglobulinas de uso intravenoso. 1.: Uso de az¨²cares como estabilizantes
%A C¨¢diz Lahens
%A Armando
%A Hern¨¢ndez Mach¨ªn
%A Janhna
%A Jo¨® S¨¢nchez
%A L¨¢zaro
%A Moya Torres
%A Aniel
%A Camero Santiesteban
%A Amador
%J Revista Cubana de Farmacia
%D 1999
%I ECIMED
%X pasteurization from the union of ii supernatants of 4 batches of normal plasma subjected to alcoholic fractionation was carried out using following stabilizers: sorbitol, sacarose and 30 % dextrose. the level of molecular aggregation wass determined by gel- filtration chromatography. sorbitol exhibited the best results with polymer formation ranging from 10 - 15 %; the values match those reported by other authors. according to who requirements, these polymers should be eliminated through other procedures for obtaining values under 10 %.
%K heat
%K esterilization [methods]
%K immunoglobulins intravenous [isolation & purification]
%K igg [isolation & purification].
%U http://scielo.sld.cu/scielo.php?script=sci_abstract&pid=S0034-75151999000200001&lng=en&nrm=iso&tlng=en