%0 Journal Article
%T Metodolog¨Şa para estudios de estabilidad qu¨Şmica en formulaciones de quitina
%A Su¨˘rez P¨Ĥrez
%A Yania
%A Almirall D¨Şaz
%A Ivone
%A Gonz¨˘lez San Miguel
%A Hilda Mar¨Şa
%A Bilbao Revoredo
%A Ofelia
%A Nieto Acosta
%A Olga M
%J Revista Cubana de Farmacia
%D 2000
%I ECIMED
%X we proposed to combine direct gravimetry as a quantitative method with infrared spectrophotometry as a supplementary qualitative technique so as to establish a methodology for monitoring chemical stability of chitin as a drug in various pharmaceutical forms: suspension, cream and suppository. the determination of chitin by gravimetric techniques was valiadated in every case according to linearity, precision, accuracy and specificity parameters. the qualitative analyses showed satisfactory results in the drug contents in time in all the evaluated formulations. these outcomes were corroborrated by infrared spectra, which showed that chitin is the only product left in filters and that it has not changed from the clinical viewpoint after two year of study.
%K chitin [chemistry]
%K drug stability
%K spectophometry
%K infrared [methods].
%U http://scielo.sld.cu/scielo.php?script=sci_abstract&pid=S0034-75152000000100002&lng=en&nrm=iso&tlng=en