%0 Journal Article
%T An¨¢lisis de algunas variables hematol¨®gicas, bioqu¨ªmicas y cl¨ªnicas en la anemia drepanoc¨ªtica. Resultados preliminares
%A Estrada del Cueto
%A Marianela
%A Garc¨ªa Caraballoso
%A Martha Beatriz
%A Cisneros Zerquera
%A Haycelvi
%A D¨ªaz Barroso
%A Liz Mabel
%A Bravo Pe£¿a
%A Marl¨¦n
%A Abreu Cruz
%A Jos¨¦
%A Espinosa Estrada
%A Edgardo E.
%A Hern¨¢ndez Padr¨®n
%A Carlos
%A Svarch
%A Eva
%A P¨¦rez Diez de los R¨ªos
%A Graciela
%A Hern¨¢ndez Mart¨ªnez
%A Ana
%A Wade Mateo
%A Maura
%A Espinosa Mart¨ªnez
%A Edgardo
%J Revista Cubana de Hematolog£¿-a, Inmunolog£¿-a y Hemoterapia
%D 2010
%I Editorial Ciencias M¨¦dicas
%X a total of 59 patients aged over 18 with sickle cell anemia were studied distributed in: group 1 (23) without acute thoracic syndrome (acs), priapism and malleolus ulcers; group 2 (39) with some of above complications. in group 2 there was a significant decrease of hemoglobin (hb) and the fetal hb and a platelet increase, lactic dehydrogenase (ldh), aspartate aminotransferase (ast), alanine aminotransferase (alt), total bilirubin (tb), alkaline phosphatase (aph), creatine kinase-mb (ck-mb) and of encephalic stroke frequency. the frequency of ast, malleolus ulcers and priapism in group 2 was of 83.3 %, 33.3 % and 50 %, respectively. the multiple linear regression analysis in all patients considering the ldh as a negati ve correlation significant for hb and the hto and positive for creatinine, ast, alt, tb, db, ib, aph and ck-mb. the pulmonary hypertension frequency was of 18.2 % (n= 10). these studies may be useful in the early diagnosis of hemolysis-related complications.
%K sickle cell anemia
%K hematological variables
%K biochemical variables
%K pulmonary hypertension.
%U http://scielo.sld.cu/scielo.php?script=sci_abstract&pid=S0864-02892010000200007&lng=en&nrm=iso&tlng=en