%0 Journal Article
%T Eficacia diagn¨®stica de sistemas de inmunoensayos para el virus de la hepatitis C en muestras de pacientes multitransfundidos
%A Rivero Jim¨¦nez
%A Ren¨¦ A.
%A Merl¨ªn Linares
%A Julio C.
%A Blanco de Armas
%A Madel¨ªn
%A Navea Leyva
%A Leonor M.
%A Lam D¨ªaz
%A Rosa M.
%A Castillo Gonz¨¢lez
%A Dunia
%A Villaescusa Blanco
%A Rinaldo
%A Gonz¨¢lez Gonz¨¢lez
%A Juan M.
%A Ballester Santovenia
%A Jos¨¦ M.
%J Revista Cubana de Hematolog£¿-a, Inmunolog£¿-a y Hemoterapia
%D 2009
%I Editorial Ciencias M¨¦dicas
%X hepatitis c virus (chv) blood-transmission is a health problem in cuba and in the world. some types of diagnostic immunoassays have been developed for the blood certification and in general have a high diagnostic sensitivity and specificity in healthy donors. however, its behavior in samples from multi-transfusion patients could by less effective. to assess the diagnostic effectiveness of the umelisa hcv third generation cuban immunoassay (tecnosuma, s.a. la habana), cuba) in samples from multi-transfusion patients, in parallel, 335 sera from patients were processed by ubi£¿ hcv eia 4.0 (united biomedical, ee.uu) and umelisa hcv third generation, and the samples with incongruous results were verified by pcr cobas ampliscreen hcv test, v2 system (roche, ee.uu.) comparing the umelisa hcv third generation system with the ubi£¿ hcv eia 4.0 it was achieved a sd of 95,8% ci(95%): 92,5-99,15 and a ed of 100% ci (95%): 99,7-100, with iy: 0,96 (0,93-0,99) with k: 0,0582 id (95%): 0,9276-0,9888, p = 0,000. both immunoassay systems were satisfactory for immunodiagnosis of multi-transfusion patients.
%K hepatitis c
%K multi-transfusions
%K immunoassay
%K diagnostic methods.
%U http://scielo.sld.cu/scielo.php?script=sci_abstract&pid=S0864-02892009000300006&lng=en&nrm=iso&tlng=en