%0 Journal Article %T Interpretaci¨®n del desempe£¿o operativo de las pruebas de tamizaje y de diagn¨®stico de enfermedades en obstetricia y ginecolog¨ªa %A Gait¨¢n-Duarte %A Hernando %A Rubio-Romero %A Jorge Andr¨¦s %A G¨®mez-Chantraine %A Margarita %J Revista Colombiana de Obstetricia y Ginecolog¨ªa %D 2009 %I Federaci¨®n Colombiana de Asociaciones de Obstetricia y Ginecolog¨ªa %X objectives: explaining how diagnostic test performanceisassessed,whetherusedforscreening or confirming a certain disease, and explaining how a diagnostic test¡¯s operational characteristics are used for reducing uncertainty about the absence or presence of the disease for which it is being used. methodology: the main concepts underlying the assessment of the performance, validity, interpretation and the use of screening and diagnostic tests' operational characteristics are addressed within a clinical context. a sample clinical scenario is then resolved using the tools provided for the reader. results: the natural history of disease, a definition of normality, percentages and ratios are essential concepts for the proper use and interpretation of a screening or a diagnostic test's operational characteristics. knowledge of pre-test probability and positive and negative likelihood ratios for a test being used is necessary for reducing uncertainty in a given diagnostic process. conclusions: interpreting a given diagnostic test's operational characteristics determines its optimal use for screening or accurately ruling out disease and thereby solving the problems we face daily in our clinical practice. %K screening %K early diagnosis %K sensitivity and specificity. %U http://www.scielo.org.co/scielo.php?script=sci_abstract&pid=S0034-74342009000400008&lng=en&nrm=iso&tlng=en