%0 Journal Article
%T Associated Factors for In-Hospital Mortality in Patients with Meningeal Cryptococcosis and HIV Infection at a Local Hospital in Lima, Peru
%A Juan C. Canessa
%A Diego Cabrera
%A Jonathan Eskenazi
%A Frine Samalvides
%J World Journal of AIDS
%P 8-14
%@ 2160-8822
%D 2011
%I Scientific Research Publishing
%R 10.4236/wja.2011.11002
%X Objective: To determine the associated factors for in-hospital mortality in patients with meningeal cryptococcosis and HIV infection at a local hospital in Lima, Perú. Materials and methods: We carried out a case-control study by reviewing the medical histories available at a local hospital in Lima, Peru. We determined the factors associated with mortality using a logistic regression model. Results: The information of 90 patients was analyzed, 37 dead and 53 alive. In the multivariate analysis we found two variables associated with mortality: Glasgow at admission (OR = 4.55 (1.61 ¨C 12.20), p = 0.01) and serum antigen titer greater than 1024 (OR = 20.48 (1.6 ¨C 261.04, p = 0.02). The protective factor found was a longer hospitalization stay (OR = 0.80 (0.69 ¨C 0.93, p = 0.005).Conclusions: A low Glasgow score and serum antigen titer greater than 1024 are associated factors with mortality, whereas hospitalization length is a protective factor.
%K Meningeal Cryptococcosis
%K Cryptococcus
%K HIV
%K Mortality
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=4378