%0 Journal Article
%T Inj¨²ria renal aguda em unidade de terapia intensiva: estudo prospectivo sobre a incid¨ºncia, fatores de risco e mortalidade
%A Ponce
%A Daniela
%A Zorzenon
%A Caroline de Pietro Franco
%A Santos
%A Nara Yamane dos
%A Teixeira
%A Ubirajara Aparecido
%A Balbi
%A Andr¨¦ Lu¨ªs
%J Revista Brasileira de Terapia Intensiva
%D 2011
%I Associa??o de Medicina Intensiva Brasileira
%R 10.1590/S0103-507X2011000300010
%X objective:to compare the clinical features and outcomes of patients with and without acute kidney injury in an intensive care unit of a tertiary university hospital and to identify acute kidney injury and mortality risk factors. methods: this was a prospective observational study of a cohort including 564 patients followed during their stay in the intensive care unit of hospital das clinicas da faculdade de medicina de botucatu (botucatu, s£¿o paulo, brazil) between may 2008 and may 2010. patients were allocated to two different groups: with (g1) and without (g2) acute kidney injury. results: the incidence of acute kidney injury was 25.5%. the groups were different with respect to the reason for admission to the intensive care unit (sepsis, g1: 41.6% versus g2: 24.1%; p < 0.0001; neurosurgery, postoperative g1: 13.8% versus g2: 38.1%; p < 0.0001); age (g1: 56.8 ¡À 15.9 vs. g2: 49.8 ¡À 17.8 years; p < 0.0001); acute physiological chronic health evaluation (apache) ii score (g1: 21.9 ¡À 6.9 versus g2: 14.1 ¡À 4.6; p < 0.0001); use of mechanical ventilation (g1: 89.2% vs. g2: 69.1%; p < 0.0001) and use of vasoactive drugs (g1: 78.3% vs. g2: 56.1%; p < 0.0001). higher rates of diabetes mellitus, congestive heart failure, chronic renal disease and use of non-steroidal anti-inflammatory drugs were more frequent in acute kidney injury patients (28.2% vs. 19.7%, p = 0.03; 23.6 vs. 11.6%, p = 0.0002; 21.5% vs. 11.5%, p < 0.0001 and 23.5% vs. 71.%, p < 0.0001, for g1 versus g2, respectively). length of hospital stay and mortality were also higher for acute kidney injury patients (g1: 6.6 ¡À 2.7 days versus g2: 12.9 ¡À5.6 days, p < 0.0001 and g1: 62.5% versus g2: 16.4%, p < 0.0001). multivariate analysis identified the following as risk factors for acute kidney injury: age above 55 years, apache ii score above 16, baseline creatinine above 1.2 and use of non-steroidal anti-inflammatory drugs (odds ratio (or) = 1.36, 95% confidence interval (95%ci): 1.22 - 1.85; or = 1.2, 95%ci: 1.11
%K acute kidney injury
%K incidence
%K risk factors
%K mortality
%K intensive care unit.
%U http://www.scielo.br/scielo.php?script=sci_abstract&pid=S0103-507X2011000300010&lng=en&nrm=iso&tlng=en