%0 Journal Article %T Diretrizes para tratamento da sepse grave/choque s¨¦ptico: abordagem do agente infeccioso - controle do foco infeccioso e tratamento antimicrobiano %A Salom£¿o %A Reinaldo %A Diament %A D¨¦cio %A Rigatto %A Otelo %A Gomes %A Brenda %A Silva %A Eliezer %A Carvalho %A No¨ºmia Barbosa %A Machado %A Flavia Ribeiro %J Revista Brasileira de Terapia Intensiva %D 2011 %I Associa??o de Medicina Intensiva Brasileira %R 10.1590/S0103-507X2011000200006 %X sepsis is a common and lethal condition that carries a substantial financial burden. in addition, it is the main cause of death in intensive care units. early diagnosis and treatment of patients has been clearly shown to improve prognosis. therefore, early diagnosis of the infecting agent, control of the primary infection site and the use of appropriate antibiotic therapy are fundamental to improving outcomes. this guideline reviews the available evidence in the literature concerning infection control and therapy strategies %U http://www.scielo.br/scielo.php?script=sci_abstract&pid=S0103-507X2011000200006&lng=en&nrm=iso&tlng=en