%0 Journal Article
%T Genetic polymorphisms of Rh, Kell, Duffy and Kidd systems in a population from the State of Paran¨¢, southern Brazil
%A Guelsin
%A Gl¨¢ucia Andr¨¦ia Soares
%A Sell
%A Ana Maria
%A Castilho
%A Lilian
%A Masaki
%A Viviane Lika
%A Melo
%A Fabiano Cavalcante de
%A Hashimoto
%A Margareth Naomi
%A Hirle
%A Loide Souza
%A Visentainer
%A Jeane Eliete Laguila
%J Revista Brasileira de Hematologia e Hemoterapia
%D 2011
%I Sociedade Brasileira de Hematologia e Hemoterapia
%R 10.5581/1516-8484.20110009
%X background: red blood group genes are highly polymorphic and the distribution of alleles varies among different populations and ethnic groups. aim: to evaluate allele polymorphisms of the rh, kell, duffy and kidd blood group systems in a population of the state of paran¨¢ methods: rh, kell, duffy and kidd blood group polymorphisms were evaluated in 400 unrelated blood or bone marrow donors from the northwestern region of paran¨¢ state between september 2008 and october 2009. the following techniques were used: multiplex-polymerase chain reaction genotyping for the identification of the rhd gene and rhce*c/c genotype; allele-specific polymerase chain reaction for the rhd¦× and restriction fragment length polymorphism polymerase chain reaction for the rhce*e/e, kel, fy-gata and jk alleles. results: these techniques enabled the evaluation of the frequencies of rh, kell, duffy and kidd polymorphisms in the population studied, which were compared to frequencies in two populations from the eastern region of s£¿o paulo state. conclusion: the rhce*c/c, fy*a/fy*b, gata-33 t/t, jk*b/jk*b genotypes were more prevalent in the population from paran¨¢, while rhce*c/c, fy*b/fy*b, gata-33 c/c, jk*a/jk*b genotypes were more common in the populations from s£¿o paulo.
%K genotype
%K polymorphism
%K genetic
%K blood group
%K brazil.
%U http://www.scielo.br/scielo.php?script=sci_abstract&pid=S1516-84842011000100009&lng=en&nrm=iso&tlng=en