%0 Journal Article %T Efectos de la suplementaci¨®n de carnitina sobre el nivel de fatiga muscular del gastrocnemio de ratas entrenadas y sedentarias %A Campos %A Rossana Gomez %A Arruda %A Miguel de %A Ramos %A Fabio Pinhero %A Cossio-Bola£¿os %A Marco Antonio %J Revista Brasileira de Cineantropometria & Desempenho Humano %D 2012 %I Scientific Electronic Library Online %R 10.5007//1980-0037.2012v14n3p324 %X l-carnitine, considered to be of great value in metabolic processes, plays an important role in the mitochondrial ¦Â -oxidation process. it may be used to improve athletic performance and to maintain a higher workload during exercise. this study aimed to investigate the effect of l-carnitine supplementation on muscle fatigue in sciatic nerve-gastrocnemius muscle preparations in sedentary and trained rats. the animals were divided into 4 groups: non-supplemented sedentary (nss), supplemented sedentary (ss), non-supplemented trained (nst), and supplemented trained (st) rats. the animals were trained in daily 1-h sessions (5 days/week) and received chronic oral l-carnitine supplementation (1 mg/ml) for 4 weeks. muscle fatigue was determined by supramaximal tetanic stimulation of the sciatic nerve (50 hz). time values for strength reduction were significantly different (p< 0.05) between nss vs. ss and nst vs. st rats. no significant differences were observed between ss vs. st and nst vs. nss rats. these findings demonstrate that l-carnitine lengthen the time required for induction of muscle fatigue. %K muscle fatigue %K supplementation %K training. %U http://www.scielo.br/scielo.php?script=sci_abstract&pid=S1980-00372012000300009&lng=en&nrm=iso&tlng=en