%0 Journal Article %T Insulinoma maligno con met¨¢stasis espl¨¦nicas: una rara observaci¨®n %A Hern¨¢ndez Benedicto %A Ren¨¦ %A Pila P¨¦rez %A Rafael %A L¨®pez P¨¦laez %A Lisel %A Pila Pel¨¢ez %A Rafael %A Holgu¨ªn Prieto %A V¨ªctor A %J Revista Archivo M£¿£¿dico de Camag£¿£¿ey %D 2009 %I Centro Provincial de Informaci¨®n de Ciencias M¨¦dicas de Camag¨¹ey %X the second case of malignant insulinoma reported in our country is presented. a 41-years female patient is admitted with the predominant clinical picture of neuroglycopenic manifestations due to severe hypoglycemias mimicking seizures and psychiatric disorders. positive results are obtained in tests of tolbutamide, glucagon, intellectual performance and prolonged fasting. in this patient, the insulinoma is not revealed through ultrasonography and ct scan. she is undergone a distal pancreatectomy with splenectomy, procedures that demonstrate the insulinoma and splenic metastasis. after surgery, the patient is free of neurologic symptoms. %K malignant insulinoma %K splenic metastasis %K neuroglycopenic symptoms. %U http://scielo.sld.cu/scielo.php?script=sci_abstract&pid=S1025-02552009000400009&lng=en&nrm=iso&tlng=en