Introduction: Prostate cancer (PC) is a malignant proliferation of prostate cells. Common screening methods, such as digital rectal examination and prostate-specific antigen (PSA) testing, lack accuracy. Magnetic resonance imaging (MRI) improves the detection, localization, and assessment of cancer progression. The objective was to document the contribution of MRI in prostate cancer screening at the Imaging and Diagnostic Center of the National Social Security Fund (CNSS) in Guinea. Methods: Descriptive study conducted from January 1, 2023, to December 31, 2023. All patients referred to our department for symptoms of prostate cancer were included in our study. The sociodemographic characteristics of the patients were collected, the MRI semiology of the anomalies was described, and the associated anomalies were identified and listed. Results: The study included 43 patients with a mean age of 68.95 years. MRI revealed specific abnormalities, including nodular foci (67.4%), lymphadenopathy (37.2%), bone metastases (30.2%). Conclusion: MRI has been shown to be effective in improving the detection and assessment of prostate cancer, providing crucial information for clinical decisions. Further studies are recommended to confirm these findings and explore therapeutic implications.
Cite this paper
Doumbouya, I. S. , Kourouma, M. , Diallo, M. and Balde, A. A. (2025). Contribution of MRI in the Diagnosis of Prostate Cancer: Study of 43 Cases at the CNSS of Guinea
. Open Access Library Journal, 12, e12537. doi: http://dx.doi.org/10.4236/oalib.1112537.
Brassart, C., Basson, L., Olivier, J., Latorzeff, I., De Crevoisier, R., Lartigau, E., et al. (2019) L’oncologue radiothérapeute, un des acteurs du parcours du patient après cancer. Surveillance après cancer de la prostate. Cancer/Radiothérapie, 23, 565-571. https://doi.org/10.1016/j.canrad.2019.07.148
Choi, Y.J., Kim, J.K., Kim, N., Kim, K.W., Choi, E.K. and Cho, K. (2007) Functional MR Im-aging of Prostate Cancer. RadioGraphics, 27, 63-75. https://doi.org/10.1148/rg.271065078
Mistry, S., Mayer, W., Khavari, R., Ayala, G. and Miles, B. (2013) Who’s Too Old to Screen? Prostate Cancer in Elderly Men. Canadian Urological Association Journal, 3, 205-210. https://doi.org/10.5489/cuaj.1071
Grosclaude, P., Belot, A., Daubisse Marliac, L., Remontet, L., Leone, N., Bossard, N., et al. (2015) Le cancer de la prostate, évolution de l’incidence et de la mortalité en France entre 1980 et 2011. Progrès en Urologie, 25, 536-542. https://doi.org/10.1016/j.purol.2015.04.011
Stephan, C., Xu, C., Brown, D.A., Breit, S.N., Michael, A., Nakamura, T., et al. (2005) Three New Serum Markers for Prostate Cancer Detection within a Percent Free PSA-Based Artifi-cial Neural Network. The Prostate, 66, 651-659. https://doi.org/10.1002/pros.20381
Akaji, E., et al. (2016) Prevalence and Predictors of Prostate Cancer Screening among Men Aged 50 Years and Older in Rabat, Morocco. Pan African Medical Journal, 25, Article 62.
Darre, T., Kpatcha,. TM., Bagny, A., Maneh, N., Gnandi-Piou, F., Tchangai, B., et al. (2017) Descriptive Epidemiology of Cancers in Togo from 2009 to 2016. Asian Pacific Journal of Cancer Prevention: APJCP, 18, 3407.
Bangbayaola, B.E. (2022) Epidemiological and Histopathological Aspects of Prostate Cancer: Data from the Mali Cancer Registry from 2016 to 2020. Master’s Thesis, University of Science, Techniques and Technologies of Bamako. https://www.bibliosante.ml/handle/123456789/5670
Koné, Y.L. (2021) Epidemiological and Histological Aspects of Prostate Tumors in the Pathological Anatomy and Cytology Department at the CHU du Point G. Master’s Thesis, University of Science, Techniques and Technologies of Bamako. https://www.bibliosante.ml/handle/123456789/4842
Hichame, N. (2022) The Contribution of MRI in the Diagnosis of Prostate Cancer Experience of the Radiology Department of the Moulay Ismail Military Hospital in Meknes (about 40 Cases). Université Sidi Mohamed Ben Abdellah de Fes.
Heidenreich, A., Bastian, P.J., Bellmunt, J., Bolla, M., Joniau, S., van der Kwast, T., et al. (2014) EAU Guidelines on Prostate Cancer. Part 1: Screen-ing, Diagnosis, and Local Treatment with Curative Intent—Update 2013. Euro-pean Urology, 65, 124-137. https://doi.org/10.1016/j.eururo.2013.09.046
Rajasekaran, A.K., Anilkumar, G. and Christiansen, J.J. (2005) Is Prostate-Specific Membrane An-tigen a Multifunctional Protein? American Journal of Physiology-Cell Physiology, 288, C975-C981. https://doi.org/10.1152/ajpcell.00506.2004
Marshall, S. and Taneja, S. (2015) Focal Therapy for Prostate Cancer: The Current Status. Prostate International, 3, 35-41. https://doi.org/10.1016/j.prnil.2015.03.007
Farasat, S., Yu, S.S., Neel, V.A., Nehal, K.S., Lardaro, T., Mihm, M.C., et al. (2011) A New American Joint Committee on Cancer Staging System for Cutaneous Squamous Cell Carcinoma: Creation and Rationale for Inclusion of Tumor (T) Characteristics. Journal of the American Academy of Dermatology, 64, 1051-1059. https://doi.org/10.1016/j.jaad.2010.08.033
Mottet, N., Bellmunt, J., Bolla, M., Briers, E., Cumberbatch, M.G., De Santis, M., et al. (2017) EAU-ESTRO-SIOG Guidelines on Prostate Cancer. Part 1: Screening, Diagnosis, and Local Treatment with Cura-tive Intent. European Urology, 71, 618-629. https://doi.org/10.1016/j.eururo.2016.08.003
Heesakkers, R.A.M., Jager, G.J., Hövels, A.M., de Hoop, B., van den Bosch, H.C.M., Raat, F., et al. (2009) Prostate Cancer: Detection of Lymph Node Metastases Outside the Rou-tine Surgical Area with Ferumoxtran-10-Enhanced MR Imaging. Radiology, 251, 408-414. https://doi.org/10.1148/radiol.2512071018
Lecouvet, F.E., Geukens, D., Stainier, A., Jamar, F., Jamart, J., d’Othée, B.J., et al. (2007) Magnetic Resonance Imaging of the Axial Skeleton for Detecting Bone Metasta-ses in Patients with High-Risk Prostate Cancer: Diagnostic and Cost-Effectiveness and Comparison with Current Detection Strategies. Journal of Clinical Oncology, 25, 3281-3287. https://doi.org/10.1200/jco.2006.09.2940
Turkbey, B., Pinto, P.A., Mani, H., Bernardo, M., Pang, Y., McKinney, Y.L., et al. (2010) Prostate Cancer: Value of Multiparametric MR Imaging at 3 T for Detection—Histopathologifc Correlation. Radiology, 255, 89-99. https://doi.org/10.1148/radiol.09090475
Rosenkrantz, A.B., Verma, S., Choyke, P.L., Eberhardt, S.C., Eggener, S., Gaitonde, K., et al. (2016) Prostate MRI and MRI-Targeted Biopsy in Patients with a Prior Negative Biopsy: A Con-sensus Statement of the American Urological Association and the Society of Ab-dominal Radiology’s Prostate Cancer Disease-Focused Panel. The Journal of Urology, 196, 1613-1618. https://doi.org/10.1016/j.juro.2016.06.079
