%0 Journal Article
%T Efeitos de baixas doses de radia£¿£¿o-X no desenvolvimento do sistema nervoso central: estudo experimental em ratos
%A Lins
%A Liliane
%A Gomes
%A La¨ªs
%A Gomes
%A Lis
%A Trindade
%A Marcele
%A Dias
%A Leonardo
%A Bragan£¿a
%A Ricardo
%A Pimentel
%A Rodrigo
%J Radiologia Brasileira
%D 2008
%I Col¨¦gio Brasileiro de Radiologia
%R 10.1590/S0100-39842008000100012
%X objective: the present study analyzes the consequences of x-irradiation for the development of the nervous system of rat fetuses. materials and methods: the sample included ten eight-week-old, pregnant rattus norvegicus albinus, wistar. five female rats constituted the control group and other five had their abdominal region exposed for 30 seconds to a single 0.3 gy radiation dose from a 70 kv, 10 ma gnatus odontological apparatus. at the 17th gestational day both groups were submitted to hysterectomy. selected sections were examined for comparative brain analysis of both groups. results: the clinical evaluation demonstrated no morphological difference between the control and the experimental groups. twenty-seven percent of the animals in the experimental group presented mild brain hemorrhage, while 73% of the animals had severe cerebral cortex hemorrhage and nervous tissue damage. none of the animals in the control group presented cerebral hemorrhage or nervous tissue damage. conclusion: these evidences demonstrate that low x-radiation doses may cause brain hemorrhage and, consequently, nervous tissue damage.
%K irradiation
%K malformations
%K hemorrhage
%K central nervous system.
%U http://www.scielo.br/scielo.php?script=sci_abstract&pid=S0100-39842008000100012&lng=en&nrm=iso&tlng=en