%0 Journal Article
%T Modulation of nociceptive-like behavior in zebrafish (Danio rerio) by environmental stressors
%A Maximino
%A Caio
%J Psychology & Neuroscience
%D 2011
%I Scientific Electronic Library Online
%R 10.3922/j.psns.2011.1.017
%X zebrafish have been demonstrated to react consistently to noxious chemical stimuli and present reliable phenotypes of stress, fear, and anxiety. in this article, we describe the modulation of nociceptive-like responses of zebrafish to fear-, stress-, and anxiety-eliciting situations. animals were exposed to an alarm substance, confinement stress, or a novel environment before being injected with 1% acetic acid in the tail. the alarm substance and confinement stress reduced the display of erratic movements and tail-beating behavior elicited by acetic acid. the novelty of the environment, in contrast, increased the frequency of tail-beating behavior. the results suggest that descending modulatory control of nociception exists in zebrafish, with apparent fear- and stress-induced analgesia and anxiety-induced hyperalgesia.
%K nociception
%K defensive behavior
%K fear
%K anxiety
%K stress
%K zebrafish.
%U http://www.scielo.br/scielo.php?script=sci_abstract&pid=S1983-32882011000100017&lng=en&nrm=iso&tlng=en