%0 Journal Article %T Homeostatic Imbalance of Purine Catabolism in First-Episode Neuroleptic-Na£żve Patients with Schizophrenia %A Jeffrey K. Yao %A George G. Dougherty Jr. %A Ravinder D. Reddy %A Matcheri S. Keshavan %A Debra M. Montrose %A Wayne R. Matson %A Joseph McEvoy %A Rima Kaddurah-Daouk %J PLOS ONE %D 2012 %I Public Library of Science (PLoS) %R 10.1371/journal.pone.0009508 %X Purine catabolism may be an unappreciated, but important component of the homeostatic response of mitochondria to oxidant stress. Accumulating evidence suggests a pivotal role of oxidative stress in schizophrenia pathology. %U http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0009508