%0 Journal Article
%T Conjugative Botulinum Neurotoxin-Encoding Plasmids in Clostridium botulinum
%A Kristin M. Marshall
%A Marite Bradshaw
%A Eric A. Johnson
%J PLOS ONE
%D 2012
%I Public Library of Science (PLoS)
%R 10.1371/journal.pone.0011087
%X Clostridium botulinum produces seven distinct serotypes of botulinum neurotoxins (BoNTs). The genes encoding different subtype neurotoxins of serotypes A, B, F and several dual neurotoxin-producing strains have been shown to reside on plasmids, suggesting that intra- and interspecies transfer of BoNT-encoding plasmids may occur. The objective of the present study was to determine whether these C. botulinum BoNT-encoding plasmids are conjugative.
%U http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0011087