%0 Journal Article %T Nucleic Acid Amplification Tests for Diagnosis of Smear-Negative TB in a High HIV-Prevalence Setting: A Prospective Cohort Study %A J. Lucian Davis %A Laurence Huang %A William Worodria %A Henry Masur %A Adithya Cattamanchi %A Charles Huber %A Cecily Miller %A Patricia S. Conville %A Patrick Murray %A Joseph A. Kovacs %J PLOS ONE %D 2012 %I Public Library of Science (PLoS) %R 10.1371/journal.pone.0016321 %X Nucleic acid amplification tests are sensitive for identifying Mycobacterium tuberculosis in populations with positive sputum smears for acid-fast bacilli, but less sensitive in sputum-smear-negative populations. Few studies have evaluated the clinical impact of these tests in low-income countries with high burdens of TB and HIV. %U http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0016321